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Tag: Pfizer Covid 19 vaccine

  • Pfizer asks US to permit children between 12 and 15 to get Covid-19 vaccine

    Drug big Pfizer and its accomplice in creating the primary Covid-19 vaccine that obtained emergency authorisation within the US wish to permit extra adolescents to obtain the vaccine.
    New York-based Pfizer and BioNTech SE of Germany have requested the US Food and Drug Administration to broaden the emergency use authorisation for his or her vaccine to incorporate adolescents ages 12 by way of 15. Back in mid-December, the two-dose shot obtained emergency clearance for vaccinating individuals aged 16 and up.
    Pfizer and BioNTech stated they’re working intently with the FDA and regulators in different international locations to get emergency or conditional authorization as shortly as doable for youths aged 12 by way of 15.
    The firms famous in a press release that preliminary outcomes by way of March 31 from late-stage testing in that age group discovered the vaccine secure and 100 per cent efficient in blocking infections. They stated negative effects had been according to these from testing of volunteers ages 16 by way of 25: ache and swelling on the injection web site, fatigue, complications, fever and nausea.

    All individuals within the research of 12- by way of 15-year-old volunteers shall be monitored for 2 years, beginning after they obtained their second dose, to look at for any issues of safety and decide how lengthy the vaccine protects recipients.

  • Pfizer says its COVID-19 vaccine protects youthful teenagers

    Pfizer introduced Wednesday that its COVID-19 vaccine is secure and strongly protecting in children as younger as 12, a step towards probably starting photographs on this age group earlier than they head again to highschool within the fall.
    Most COVID-19 vaccines being rolled out worldwide are for adults, who’re at greater danger from the coronavirus. Pfizer’s vaccine is permitted for ages 16 and older. But vaccinating kids of all ages will probably be vital to stopping the pandemic — and serving to colleges, a minimum of the higher grades, begin to look somewhat extra regular after months of disruption.
    In a examine of two,260 U.S. volunteers ages 12 to fifteen, preliminary knowledge confirmed there have been no circumstances of COVID-19 amongst absolutely vaccinated adolescents in comparison with 18 amongst these given dummy photographs, Pfizer reported.
    It’s a small examine, that hasn’t but been revealed, so one other vital piece of proof is how effectively the photographs revved up the youngsters’ immune programs. Researchers reported excessive ranges of virus-fighting antibodies, considerably greater than had been seen in research of younger adults.
    Kids had negative effects just like younger adults, the corporate stated. The foremost negative effects are ache, fever, chills and fatigue, significantly after the second dose. The examine will proceed to trace individuals for 2 years for extra details about long-term safety and security.
    Pfizer and its German accomplice BioNTech within the coming weeks plan to ask the U.S. Food and Drug Administration and European regulators to permit emergency use of the photographs beginning at age 12.
    “We share the urgency to expand the use of our vaccine,” Pfizer CEO Albert Bourla stated in a press release. He expressed “the hope of starting to vaccinate this age group before the start of the next school year” within the United States.
    Pfizer isn’t the one firm in search of to decrease the age restrict for its vaccine. Results are also anticipated quickly from a U.S. examine of Moderna’s vaccine in 12- to 17-year-olds.
    But in an indication that the findings had been promising, the FDA already allowed each firms to start U.S. research in kids 11 and youthful, working their option to as younger as 6-month-old.
    AstraZeneca final month started a examine of its vaccine amongst 6- to 17-year-olds in Britain. Johnson & Johnson is planning its personal pediatric research. And in China, Sinovac lately introduced it has submitted preliminary knowledge to Chinese regulators displaying its vaccine is secure in kids as younger as 3.

  • EU procures further 300 million doses of Pfizer’s Covid-19 vaccine

    The European Union on Friday secured a deal for an extra 300 million doses of the Covid-19 vaccine developed by Pfizer and BioNTech in an try to allow member nations to ramp up their vaccination programmes. President of the European Commission Ursula von der Leyen stated the transfer was a “very positive development.”“We right now have access to 300 million doses of the BioNTech-Pfizer vaccine. We now have agreed with BioNTech-Pfizer to extend the contract. With the new agreement, we could purchase a total of up to an additional 300 million doses of the vaccine. In other words, this will allow us to double the number of doses,” Von der Leyen stated.Moreover, 75 million of those new doses can be accessible by the second quarter of the yr and the remaining doses can be delivered within the third and fourth quarters, she added. Von der Leyen additionally stated that the vaccine has already been permitted by Europe’s regulator, the European Medicines Agency (EMA), and would subsequently require no new negotiations for the deal. Also, the vaccine has been authorised already thus making it simpler for the member states to proceed their inoculation program, she added.On Wednesday, Europe granted its approval to Moderna’s Covid-19 vaccine, the second in European Union. “With these two authorised vaccines, we have already secured a number of doses that we need to vaccinate 380 million Europeans. This is more than 80 per cent of the European population,” von der Leyen added. She additionally expressed the idea that different vaccines would even be permitted within the “coming weeks and months.”When requested if particular person member nations of the EU can be allowed to barter their very own offers with vaccine producers, von der Leyen stated “There will be no parallel negotiations; no parallel contracts. The framework we are all working in is a framework of 27 [nations]. Together we are negotiating, together we are procuring.”Earlier on Monday, Germany stated that the nation has signed a memorandum of understanding with BioNTech for supplying 30 million doses of their vaccine on a bilateral foundation. The nation additionally stated that the EU was conscious of the MoU, in response to a information report by Reuters.

  • Pfizer’s vaccine can defend towards coronavirus variant: Study

    Image Source : AP Pfizer research suggests vaccine works towards coronavirus variant
    New analysis means that Pfizer’s COVID-19 vaccine can defend towards a mutation present in two extremely contagious variants of the coronavirus that erupted in Britain and South Africa. Those variants are inflicting world concern. They each share a standard mutation known as N501Y, a slight alteration on one spot of the spike protein that coats the virus. That change is believed to be the rationale they’ll unfold so simply.

    Most of the vaccines being rolled out world wide prepare the physique to acknowledge that spike protein and struggle it. Pfizer teamed with researchers from the University of Texas Medical Branch in Galveston for laboratory checks to see if the mutation affected its vaccine’s capability to take action.

    They used blood samples from 20 individuals who acquired the vaccine, made by Pfizer and its German associate BioNTech, throughout a big research of the photographs. Antibodies from these vaccine recipients efficiently fended off the virus in lab dishes, in accordance with the research posted late Thursday on a web based website for researchers.

    The research is preliminary and has not but been reviewed by specialists, a key step for medical analysis.

    But “it was a very reassuring finding that at least this mutation, which was one of the ones people are most concerned about, does not seem to be a problem” for the vaccine, stated Pfizer chief scientific officer Dr. Philip Dormitzer.

    READ MORE: WHO clears Pfizer-BioNTech COVID vaccine for emergency use

    Viruses continually bear minor modifications as they unfold from individual to individual. Scientists have used these slight modifications to trace how the coronavirus has moved across the globe because it was first detected in China a few yr in the past.

    British scientists have stated the variant discovered within the U.Ok. – which has grow to be the dominant kind in components of England — nonetheless gave the impression to be vulnerable to vaccines. That mutant has now been discovered within the U.S. and quite a few different international locations.

    But the variant first found in South Africa has a further mutation that has scientists on edge, one named E484K.

    The Pfizer research discovered that the vaccine appeared to work towards 15 extra potential virus mutations, however E484K wasn’t amongst these examined. Dormitzer stated it’s subsequent on the listing.

    READ MORE: Pfizer prepares for COVID-19 vaccine rollout, largest vaccination effort in US historical past

    Dr. Anthony Fauci, the highest U.S. infectious illness professional, just lately stated vaccines are designed to acknowledge a number of components of the spike protein, making it unlikely a single mutation may very well be sufficient to dam them. But scientists world wide are conducting analysis with completely different vaccines to seek out out.

    Dormitzer stated if the virus finally mutates sufficient that the vaccine wants adjusting – very similar to flu photographs are adjusted most years – that tweaking the recipe wouldn’t be troublesome for his firm’s shot and comparable ones. The vaccine is made with a bit of the virus genetic code, easy to modify, though it’s not clear what sort of extra testing regulators would require to make such a change.

    Dormitzer stated this was solely the start “of ongoing monitoring of virus changes to see if any of them might impact on vaccine coverage.”

    ALSO READ | Second pan-India dry run immediately, first vaccine photographs early subsequent week: All you must know

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  • UK vaccines might finish Covid-19 lockdowns from February: Mail

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    Lockdowns within the UK might end by the top of February as soon as a bunch of as much as 15 million susceptible folks have been vaccinated, the Mail on Sunday reported, citing authorities sources.The nation’s well being service would now not be liable to being overwhelmed by Covid-19 circumstances as soon as that threshold is met, the newspaper mentioned. The UK turned the primary nation in Western Europe to start vaccinations, when it began utilizing the Pfizer Inc. and BioNTech SE shot on Dec. 8. More than 600,000 folks have been vaccinated via Dec. 20.The nation has been one of many hardest hit in Europe with greater than 70,000 deaths, probably the most within the area after Italy. Much of the UK has been moved into the harshest Tier 4 restrictions, which prohibit family mixing and compelled the closing of pubs, eating places and plenty of companies after the invention earlier this month of a extra contagious pressure of the virus.The vaccine developed by the University of Oxford and AstraZeneca Plc shall be rolled out throughout the UK beginning Jan. 4, the Sunday Telegraph reported, citing plans that ministers are drawing up. The authorities is hoping that 2 million folks will get their first dose of one of many vaccines inside two weeks of the roll-out of the AstraZeneca shot, the paper mentioned.The Sun newspaper reported that regulators will approve the vaccine as early as Dec. 28. Responding to the report, a Health Department spokesperson mentioned by electronic mail that the Medicines and Healthcare Products Regulatory Agency will want time to hold out a overview of the vaccine knowledge.The Telegraph additionally reported that mass vaccination facilities at sports activities stadiums and convention venues are anticipated to launch within the second week of January. The Oxford vaccine is simpler to retailer and deal with than the one from Pfizer, making it simpler to achieve folks in secluded components of the nation.The newspaper mentioned that authorities officers are making ready to carry a vital assembly on the pandemic Monday after scientists warned that faculty closures could also be essential to sluggish the unfold of the brand new Covid-19 variant.The charge at which the virus is growing, generally known as the R quantity, is estimated at 1.1 to 1.3 as of Dec.24, in keeping with the most recent authorities knowledge. A studying above 1.0 signifies the unfold of the virus is accelerating. The UK reported 34,693 extra circumstances and 210 deaths on Dec. 26.

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